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微血管疾病、外周动脉疾病会增加截肢风险数十倍!糖尿病人要注意

根据美国心脏协会杂志Circulation最近的一项研究,与没有疾病的患者相比,微血管疾病高度独立于腿部截肢的风险。我们为大多数糖尿病朋友建立了健康咨询和康复交流小组。有专家和营养师在线指导,以及营养餐,试纸和其他奖品。您可以私下订阅:糖尿病,获取联系信息!

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首先,该研究涉及125,000人

该研究由美国心脏协会的血管疾病战略研究网络和美国退伍军人事务部资助,研究微血管疾病或外周动脉疾病(PAD)患者或微血管疾病和PAD两者的截肢风险。研究人员使用了退伍军人老龄化队列研究的数据,其中包括超过125,000名退伍军人,他们最初在研究开始时没有截肢。

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二,微血管病变,外周动脉疾病明显增加下肢截肢的风险

在平均9年中,微血管疾病患者在研究期间下肢截肢风险增加3.7倍,截肢风险增加18%;

下肢截肢的风险增加了13.9倍,截肢率为22%。下肢截肢微血管病和PAD的风险增加了23倍,占所有截肢的45%。

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三,外周动脉疾病(PAD)

PAD是远离心脏的动脉狭窄,通常存在于腿部。走路或爬楼梯时,可能会导致腿部肌肉痉挛,疼痛或疲劳。如果不及时治疗,PAD可引起坏疽和截肢。

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四,微血管病

In microvascular disease, tiny blood vessels that carry blood to the muscles and other tissues of the body no longer function properly. Although the disease is usually diagnosed in the eye (retinopathy) or kidney (kidney disease), the authors believe that these are markers of microvascular dysfunction throughout the body, especially in diabetics.

The study raises the view that microvascular disease is a systemic disease, not just a part of the body.

5. PAD (legs) are at higher risk for other cardiovascular diseases

“PAD (legs) has long been thought to be a sign that patients may also shrink arteries that cause the heart or brain. If patients have PAD, they are at higher risk for other cardiovascular diseases, such as heart attacks and strokes, "Beckman said. "Our research has shown that microvascular disease in any part of the body, such as the eyes, kidneys or feet (neuropathy) may be associated with decreased vascular function in other parts of the body, leaving patients at risk of potential lower extremity amputation."

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6. Foot care is very important

Based on the findings, Beckman recommends that patients with microvascular disease need to closely observe and care for their feet to detect pain or injury early to promote healing and reduce amputation. "Patients with microvascular disease and PAD have the highest risk of lower extremity amputation and require maximum medication to reduce the risk," Beckman said.

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